With the win over Ioa, Northwestern is guaranteed to have its 4th consecutive year without a losing season. While that might not sound very impressive, 78 other programs have had a losing season more recently. They are:
Wake Forest
Duke
Minnesota
Kansas
UAB
Memphis
Rice
Buffalo
Bowling Green
Akron
Ball State
Central Michigan
Eastern Michigan
Washington State
Vanderbilt
North Texas
Western Kentucky
ULL
New Mexico State
San Jose State
UNLV
Colorado State
New Mexico
Wyoming
2009
Maryland
North Carolina State
Virginia
Colorado
Baylor
Texas A&M
Michigan State
Purdue
Illinois
Michigan
Indiana
Tulsa
UTEP
Tulane
Louisville
Syracuse
San Diego State
Washington
Arizona State
Miami (OH)
Toledo
Kent State
Western Michigan
Florida Atlantic
Arkansas State
Florida International
Mississippi
Louisiana Tech
Utah State
Hawaii
Army
2008
Iowa State
Kansas State
Temple
Ohio
Northern Illinois
Stanford
UCLA
UCF
Marshall
SMU
Tennessee
Auburn
Arkansas
Middle Tennesee State
Louisiana-Monroe
Idaho
2007
North Carolina
Miami (FL)
Kansas
Nebraska
Pittsburgh
Notre Dame
Arizona
Nevada
Six other programs had their most recent losing season in 2006:
Fresno State
Mississippi State
Alabama
Air Force
Connecticut
Iowa
In addition, 18 other programs haven't had a losing season since before 2006, but might have one this year (* means that they almost certainly won't reach .500)
Boston College
Clemson
Georgia Tech
Texas Tech
Texas*
South Florida
Rutgers
West Virginia
Cincinnati*
Penn State
Houston
Army
BYU
Oregon State*
California
Florida
Georgia
Troy
To sum up, 102 of the 119 other FBS programs have either had a losing season as recently as Northwestern or are at risk for it this year.